First Author     Title     Journal Year     DOI PubMed
De Caro, A. Characterization of a protein isolated from pancreatic calculi of men suffering from chronic calcifying pancreatitis Biochemical and Biophysical Research Communications 1979   111670
De Caro, A. The human pancreatic stone protein Biochimie 1988   3147713
Giorgi, D. Secretory pancreatic stone protein messenger RNA. Nucleotide sequence and expression in chronic calcifying pancreatitis Journal of Clinical Investigation 1989   2525567
Provansal-Cheylan, M. Pancreatic stone protein: quantification in pancreatic juice by enzyme-linked immunosorbent assay and comparison with other methods Pancreas 1989   2510147
Bernard, J.P. Quantification of human lithostathine by high performance liquid chromatography Gut 1995   7737575
Hayakawa, T.  Pancreatic stone protein and lactoferrin in human pancreatic juice in chronic pancreatitis Pancreas 1995   7716137
Mariani, A. Purification and assay of secretory lithostathine in human pancreatic juice by fast protein liquid chromatography Gut 1995   7737574
Hawrami, K.  Analysis of islet regenerating (reg) gene polymorphisms in fibrocalculous pancreatic diabetes Pancreas 1997   9057183
Yamadera, K. Quantification of human lithostathine S2-5 forms using the antibody to the N-terminal peptide region Pancreas 1998   9598807
Sobajima, H. Urinary excretion of pancreatic stone protein in diabetic nephropathy Internal Medicine 1998   9678681
Duplan, L. Lithostathine and pancreatitis-associated protein are involved in the very early stages of AlzheimerÕs disease Neurobiology of Aging 2001   11164279
Jin, C. X.  Pancreatic stone protein of pancreatic calculi in chronic calcified pancreatitis in man Jop: Journal of the Pancreas 2002   11884767
Yonemura, Y. REG gene expression is associated with the infiltrating growth of gastric carcinoma Cancer 2003   14508825
Shervani, N. J. Autoantibodies to REG, a beta-cell regeneration factor, in diabetic patients European Journal of Clinical Investigation 2004   15530148
Lefler, D. M. Identification of proteins in slow continuous ultrafiltrate by reversed-phase chromatography and proteomics Journal of Proteome Research 2004   15595735
Sekikawa, A. REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer Gastroenterology 2005   15765400
Farnbacher, M. J. Composition of clogging material in pancreatic endoprostheses Gastrointestinal Endoscopy 2005   15933688
Narasimhulu, K. V.  Structural studies of the biomineralized species of calcified pancreatic stones in patients suffering from chronic pancreatitis Biophysical Chemistry 2005   15829347
Sekikawa, A. Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer Gut 2005   15914572
Yuan, R. H.  Opposite roles of human pancreatitis-associated protein and REG1A expression in hepatocellular carcinoma: association of pancreatitis-associated protein expression with low-stage hepatocellular carcinoma, beta-catenin mutation, and favorable prognosis Clinical Cancer Research 2005   15814635
Kiji, T. Activation of regenerating gene Reg in rat and human hearts in response to acute stress. American Journal of Physiology 2005   15778284
Nabi, G.  Proteomic analysis of urine in patients with intestinal segments transposed into the urinary tract Proteomics 2005   15765495
Motoyama, S. REG I expression predicts long-term survival among locally advanced thoracic squamous cell esophageal cancer patients treated with neoadjuvant chemoradiotherapy followed by esophagectomy. Surgical Oncology 2006   17009160
Stejskal, D.  Our experiences with measurement of new potential biomarkers in the diagnosis of latent forms of myocardial ischemia Biomedical Papers of the Medical Faculty of Palacky University in Olomouc, Czech Republic 2006   17426785
Mahurkar, S. Comprehensive screening for reg1alpha gene rules out association with tropical calcific pancreatitis World Journal of Gastroenterology 2007   17990360
Csillag, C. Expression of the genes dual oxidase 2, lipocalin 2 and regenerating islet-derived 1 alpha in Crohn's disease Scandinavian Journal of Gastroenterology 2007   17454855
Kaneko, K. Proteomic analysis of protein plugs: causative agent of symptoms in patients with choledochal cyst Digestive Diseases & Sciences 2007   17415647
Astrosini, C.  REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis International Journal of Cancer 2008   18452172
Chinuki, D. REG Ialpha protein expression in Barrett's esophagus Journal of Gastroenterology & Hepatology 2008   18289358
Hayashi, K. REG Ialpha is a reliable marker of chemoradiosensitivity in squamous cell esophageal cancer patients Annals of Surgical Oncology 2008   18259819
Minamiya, Y.  REG1A expression is an independent factor predictive of poor prognosis in patients with non-small cell lung cancer Lung Cancer 2008   17964685
Sasaki, Y. REG1A expression is an independent factor predictive of poor prognosis in patients with breast cancer Annals of Surgical Oncology 2008   18781363
Keel, M. Pancreatic stone protein is highly increased during posttraumatic sepsis and activates neutrophil granulocytes Critical Care Medicine 2009 10.1097/CCM.0b013e31819da7d6. 19325491
Yamagishi, H. Expression profile of REG family proteins REG Ialpha and REG IV in advanced gastric cancer: comparison with mucin phenotype and prognostic markers Modern Pathology 2009   19329938
Kimura, T. Involvement of REG Ialpha protein in the regeneration of ductal epithelial cells in the minor salivary glands of patients with Sjogren's syndrome Clinical & Experimental Immunology 2009   19016805
Kaneko, K. Acidic and basic solutions dissolve protein plugs made of lithostathine complicating choledochal cyst/pancreaticobiliary maljunction Digestive Diseases & Sciences 2009   18989781
Sekikawa, A. Involvement of the IL-22/REG Ialpha axis in ulcerative colitis Laboratory Investigation 2010   20065946
Zhou, L. Upregulation of REG Ialpha accelerates tumor progression in pancreatic cancer with diabetes International Journal of Cancer 2010   20099282
Park, J. Y.  Proteomic analysis of pancreatic juice for the identification of biomarkers of pancreatic cancer Journal of Cancer Research & Clinical Oncology 2011   21691750
Boeck, L. Pancreatic stone protein: a marker of organ failure and outcome in ventilator-associated pneumonia Chest 2011 10.1378/chest.11-0018. 21835904
Peterson, K. M. The expression of REG 1A and REG 1B is increased during acute amebic colitis Parasitology International 2011   21586335
Que, Y. A. Pancreatic stone protein as an early biomarker predicting mortality in a prospective cohort of patients with sepsis requiring ICU management Critical Care 2012 10.1186/cc11406. 22748193
Sim, W. H. Expression profile of genes involved in pathogenesis of pediatric Crohn's disease Journal of Gastroenterology & Hepatology 2012   22098497
Bacon, S.  Serum levels of pancreatic stone protein (PSP)/reg1A as an indicator of beta-cell apoptosis suggest an increased apoptosis rate in hepatocyte nuclear factor 1 alpha (HNF1A-MODY) carriers from the third decade of life onward BMC Endocrine Disorders 2012   22808921
Llewelyn, M. J. Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care Critical Care 2013 10.1186/cc12588. 23531337
Schlapbach, L. J.  Pancreatic stone protein as a novel marker for neonatal sepsis Intensive Care Medicine 2013 10.1007/s00134-012-2798-3. 23296629
Gukasjan, R.  Pancreatic stone protein predicts outcome in patients with peritonitis in the ICU Critical Care Medicine 2013 10.1097/CCM.0b013e3182771193. 23399938
Scherr, A. Pancreatic stone protein predicts positive sputum bacteriology in exacerbations of COPD Chest 2013 10.1378/chest.12-0730. 22922487
Ruiz-Ortiz, E.  Urinary levels of regenerating protein Ialpha do not differentiate celiac patients and healthy subjects Biomarkers 2013   23312007
Kofanova, O. A. Lithostatine concentration is not useful for assessing the preanalytical variations in biobanked urine samples Biopreservation and Biobanking 2013   24835263
Jiri, Z. Pancreatic stone protein - a possible biomarker of multiorgan failure and mortality in children sepsis Cytokine 2014   24594294
Yang, J. Pancreatic stone protein/regenerating protein (PSP/reg): a novel secreted protein up-regulated in type 2 diabetes mellitus Endocrine 2014 10.1007/s12020-014-0427-3. 25234740
Aida, K. Distinct cell clusters touching islet cells induce islet cell replication in association with over-expression of Regenerating Gene (REG) protein in fulminant type 1 diabetes PLoS ONE 2014   24759849
Hofmann, B. T. ABO Blood Group IgM isoagglutinins interact with tumor-associated O-glycan structures in pancreatic cancer Clinical Cancer Research 2014   25320359
Pan, S. Proteomics analysis of bodily fluids in pancreatic cancer Proteomics 2015   25780901
Que, Y. A. Prognostication of mortality in critically Ill patients with severe infections Chest 2015 10.1378/chest.15-0123 26065577
Schlapbach, L. J. Normal values for pancreatic stone protein in different age groups BMC Anesthesiology 2015 10.1186/s12871-015-0149-y. 26588901
Klein, Holger J. Pancreatic Stone Protein Predicts Postoperative Infection in Cardiac Surgery Patients Irrespective of Cardiopulmonary Bypass or Surgical Technique PLoS One 2015   25793700
Palmiere, C. Pancreatic stone protein as a postmortem biochemical marker for the diagnosis of sepsis Legal Medicine 2015   25205512
Park, J. Discovery and validation of biomarkers that distinguish mucinous and nonmucinous pancreatic cysts Cancer Research 2015   26122842
Rass, AA. The Role of Pancreatic Stone Protein in Diagnosis of Early Onset Neonatal Sepsis. BioMed Research International 2016   27689072
Aboshanif, M. Prognostic role of regenerating gene-I in patients with stage-IV head and neck squamous cell carcinoma. Diagnostic Pathology 2016   27539087
Geng, J. Decreased REG1α expression suppresses growth, invasion and angiogenesis of bladder cancer. European Journal of Surgical Oncology 2017   28209239
Xing, H. Role of regenerating gene IA expression on local invasion and survival in nasopharyngeal carcinoma. Biological Research 2017   29162157
Garc’a de Guadiana-Romualdo, L. Pancreatic stone protein and soluble CD25 for infection and sepsis in an emergency department. European Journal of Clinical Investigation 2017   28155994
Wu, Q. Prognostic Value of High-Sensitivity C-Reactive Protein, Procalcitonin and Pancreatic Stone Protein in Pediatric Sepsis. Medical Science Monitor 2017   28358790
Cui, C. Procalcitonin and Pancreatic Stone Protein Function as Biomarkers in Early Diagnosis of Pediatric Acute Osteomyelitis. Medical Science Monitor 2017   29091592
Tsuchida, C. Expression of REG family genes in human inflammatory bowel diseases and its regulation. Biochemistry and Biophysics Reports 2017   29090282
Li, L. Elevated serum level of pancreatic stone protein/regenerating protein (PSP/reg) is observed in diabetic kidney disease. Oncotarget 2017 10.18632/oncotarget.16369. 28418911
Roth, L. Systemic inflammatory response after hyperthermic intraperitoneal chemotherapy (HIPEC): The perfusion protocol matters! Eur J Surg Oncol 2019 10.1016/j.ejso.2019.03.036 30954352
Zhu, X Association of Serum PSP/REG Iα with Renal Function in Pregnant Women BioMed Research International 2019 10.1155/2019/6970890. 31139647
Klein, J.H. Pancreatic Stone Protein Predicts Sepsis in Severely Burned Patients Irrespective of Trauma Severity: A Monocentric Observational Study Annals of Surgery 2020 10.1097/SLA.0000000000003784 31972652
Klein, J.H. Response of routine inflammatory biomarkers and novel Pancreatic Stone Protein to inhalation injury and its interference with sepsis detection in severely burned patients Burns 2020 0.1016/j.burns.2020.04.039 33272743
Klein, J.H. Expression of Pancreatic Stone Protein is Unaffected by Trauma and Subsequent Surgery in Burn Patients World Journal of Surgery 2020 10.1007/s00268-020-05589-w 32451625